TARGETED MUTATIONS IN THE FUSION PEPTIDE REGION OF LA CROSSE VIRUS ATTENUATE NEUROINVASION AND CONFER PROTECTION AGAINST ENCEPHALITIS

Targeted Mutations in the Fusion Peptide Region of La Crosse Virus Attenuate Neuroinvasion and Confer Protection against Encephalitis

La Crosse virus (LACV) is a major cause of pediatric encephalitis and aseptic meningitis in the Midwestern, Mid-Atlantic, and Southern United States, where it is an emerging pathogen.The LACV Gc glycoprotein plays a critical role in the neuropathogenesis of LACV encephalitis as the putative virus attachment protein.Previously, we identified and exp

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Extension of Einstein Average Aggregation Operators to Medical Diagnostic Approach Under q-Rung Orthopair Fuzzy Soft Set

The macallan hip flask paradigm of the soft set (SS) was pioneered by Moldotsov in 1999 by prefixing the parametrization tool in accustomed sets, which yields general anatomy in decision-making (DM) problems.The q-rung orthopair fuzzy soft set (q-ROFSS) is an induced form of the intuitionistic fuzzy soft set (IFSS) and Pythagorean fuzzy soft set (P

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Road traffic related mortality in Vietnam: Evidence for policy from a national sample mortality surveillance system

Abstract Background Road traffic injuries (RTIs) are among the leading causes of mortality in Vietnam.However, mortality data collection systems in Vietnam in general and for RTIs in particular, remain inconsistent and incomplete.Underlying distributions of external causes and body injuries are not available from routine data collection systems or

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